Debris of the aircraft lies on the ground. Rachel Wisniewski/Reuters (CNN)

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SOURCE: CNN

A twin-engine medevac jet carrying a child patient and her mother crashed in a neighborhood in northeast Philadelphia Friday night, causing a fiery explosion, according to authorities and video from the scene.

The Learjet 55 with six people on board crashed after departing from Northeast Philadelphia Airport.

On board was a pediatric patient and her mother, returning home to Mexico after the child had been treated in Philadelphia, said Shai Gold, spokesperson for flight operator Jet Rescue Air Ambulance.

The downed Learjet was en route to Springfield-Branson National Airport in Missouri, the FAA said. It was reported that the flight planned to stop for refueling at the Springfield airport before continuing to its final destination of Tijuana, Mexico.

Also on board were four crew members, Gold said – a pilot, co-pilot, paramedic and doctor. All six people on board were Mexican nationals, according to Mexico’s foreign ministry.

“At this time, we cannot confirm any survivors,” the air ambulance company said earlier Friday.

The plane took off just after 6 p.m. ET and reached 1,650 feet before plunging, according to data from ADS-B Exchange. The data shows the final speed of descent was 11,000 feet per minute.

As an air traffic controller tries to contact the plane, there’s a callout, heard on LiveATC.net, “Medevac med service, northeast tower. Medevac med service, northeast tower. Are you on frequency?”

A little over a minute later, the controller is heard saying: “We have a lost aircraft.”

Several houses and vehicles “were impacted,” Philadelphia Mayor Cherelle Parker said at a news conference Friday evening, but added that “we have no reports on the number of fatalities.”